PGDMLT Most Imp Mcqs | SEROLOGY AND HISTOPATHOLOGY | PGDMLT MCQs | Mcqs with ans lab technician

SEROLOGY AND HISTOPATHOLOGY MCQs & Ans

1) Name the most commonly used monoclonal antibody for treatment of breast cancer?

A) Bradikinins

B) Prostaglandin

C) Erbutir

D) Herceptin - Ans 

2) Name the syndrome occur in children due to deficiency of the thymus.

A) Acromegaly

B) Gigantism

C) Cushing syndrome

D) DiGeorge syndrome - Ans 

3) Name the cytokines which act as a t cell growth factor?

A) IL-3

B) IL-2 - Ans

C) IL-4

D) IL-5

4) Name the drug which is used to isolate hybridoma cell from the media?

A) Amphetamine

B) Opium

C) Aminopterin - Ans

D) Cocaine

5) Which of the following acts as a coreceptor for B cell activation?

A) CD28

B) IL-2

C) IgA

D) CD19 - Ans

6) Which of the following immunity is obtained during a lifetime?

(a) Acquired immunity- Ans

(b) Active immunity

(c) Passive immunity

(d) None of the above.

7) Hepatitis is an example of _______.

(a) Subunit Vaccine

(b) Killer Vaccine

(c) Toxoids Vaccine

(d) Recombinant Vaccine - Ans

8) Which of the following statements is true about the IgM of humans ?

(a) IgM can cross the placenta

(b) IgM can protect the mucosal surface

(c) IgM is produced by high-affinity plasma cells

(d) IgM is primarily restricted in the circulation - Ans

9) Interferons are..........

(a) Cytokine barriers - Ans

(b) Physical barriers

(c) Cellular barriers

(d) Physiological barriers

10) Which of the following cells of the immune system do not perform phagocytosis ?

(a) Macrophage

(b) Neutrophil

(c) Eosinophil

(d) Basophil - Ans

11) The phenomenon of selective proliferation of B cell in response to their interaction with the antigen is called...

A) clonal expansion

B) monoclonal selection

C) clonal proliferation

D) clonal selection - Ans

12) antibodies are......

A) opsonins - Ans

B) lipoproteins

C) serum phagocytes

D) none of these

13) INFY are primarily produced by... 

A) NK cells

B) TH-1 cells

C) Macrophages

D) both a & c - Ans

14) presence of _______ can be used to separate helper t cells from cytotoxic t cells

A) class 2 MHC

B) CD-2

C) CD-3

D) CD-4 - Ans

15) Cytokines are small cell-signaling protein molecules that are secreted by the immune system and also by glial cells of the

 A) nervous system - Ans

 B) muscular system

 C) endocrine system

 D) reproductive system

16) Example of Cytokines.......

 A) BDNF

 B) EGF

 C) FGP

 D) All - Ans

17) Name of BDNF

A) Brain derived neurotrophic factor - Ans

B) Bronch derived neurotropic factor

C) none

18) Which of the following is considered an anti-inflammatory cytokine?

A) INF-gamma

B) IL-1b

C) IL-4

D) IL-10 - Ans

19) Macrophage activation to kill intracellular pathogens is primarily mediated by

A) IL-2

B) IFN - Ans

C) GM-CSF

D) IL-12

20) Which of the following is a coconut milk factor.

(a) cytokinin - Ans

(b) morphological

(c) auxin

(d) none

21) The first one to synthesize cytokines was

A) Thimman and went

B) calvin

C)Letham

D) Skoog and miller - Ans

22) The hormons cytokinin’s has the main function of.......

A) causing dormancy

B) cell movement

C) participating in cell division

D) induction of cell division and delay in senescence - Ans

23) Which of the following class of cytokines receptor unilize G - protein coupled receptor for it's downstream function ?

A) chemokines receptor - Ans

B) Hematopoietic receptor

C) Interferon receptor

D) none

24) TNF is an endogenous pyrogen that induces fever. which of the following statement is true regarding TNF expect.

A) TNF induces IL-1 production for induction of fever

B) TNF induces the synthesis of prostaglandin

C) TNF induces production acute phase protein

D) TNF level is lower in septic stock - Ans

25) Which of the following cytokines is used for the treatment of viral hepatitis and multiple sclerosis ?

A) INF-alpha

B) INF- beta - Ans

C) INF- gamma 

D) TNF

26) Cytokines recognise and engage with their receptor for biological action.which of the following is the correct sequence of high- affinity to low_ affinity international?

A) antibody>MHC >cytokines

B) MHC> Antibody> cytokines

C) cytokines>Antibody>MHC - Ans

D) none

27) EPO is a........

A) glycoprotein - Ans

B) glycogen

C) a and b

D) none

28) BDNF itself is important for

A) long terms memory - Ans

B) small terms memory

C) a and b

D) none

29) PDGF is one of the......

A) numerous growth factor - Ans

B) angiogenesis growth

C) morphological growth

D) cell mediated growth

30) FGFs full Form

A) FIBROBLASTS GROWTH FACTOR - Ans

B) FIBRINOGEN GROWTH FACTOR

C) a and b

D) none

31) Infs are Protein made and release by.......

A) lymphocytes - Ans

B) cytokinesis

C) Tumor cells

D) none

32) PDGF play's a role in

A) embryonic development - Ans

B) actively cell

C) cell mediated immune

D) EPO

33)  ISGs full form

A) interferon stimulated genes - Ans

B) infused server gene

C) A and b

D) none

34) Proteasomes are Protein complexes present in a

A) cell - Ans

B) plasmid

C) Members

D) macrophages

35)  Which word best deseribes peptide mediators or intercellular Messenger which regulate immunological, inflammatory and reparative host response ?

A) Monokiness

B) Lymphokiness

C) Cyyokines - Ans

D) Intakinen

36) All of the following are autoimmune disorders except..

 A)Graves disease

 B) Rheumatoid arthritis - Ans

 C) SCID

 D) Addison’s disease

37) HIV attacks

 A) T helper cells - Ans

 B) B cells

 C) T cytotoxic cells

 D) Macrophages

38) SCID can occur due to the absence of enzyme

 A) adenosine deminase - Ans

 B) guanosine deminase

 C) Phosphorlyaqes

 D) Thymidine deminase

39) Which of the following antibodies is predominality present in tears,

Saliva and mucous.

A) IgM

B) IgG

C) IgE

D) IgA - Ans

40)___ is a cocount milk factor.

A) Morphactin

B) cytokinin - Ans

C) Morphactin

D) auxin

41) Which of the following cells of the immune system do not perform phagocytosis?

A) Macrophage

B) Neutrophil

C) Eosinophil

D) Basophil - Ans

 42) The common disorders caused by a poor immune system include___

 A) Epidemic disease - Ans

 B) Deficiency disease

 C) autoimmune disorder

 D) None 

43) Oral polio drops contain......

 A) havested antibodies

 B) activated patjogeni

 C) Attenutated pathogens - Ans

 D) gamma globulins 

44) B cells have ___ antibodies bound to is surface.

 A) 50,000 to 100,000 - Ans

 B) 40,000

 C) 10,000

 D) 100 to 1000

45) Which are present in serum before viral infection...

 A) Natural antibodies - Ans

 B) Immunoglobin

 C) Domin

 D) None

46) B-cell receptor consist of memebrabe-bound immunoglobulin and a small heterodimer protein for signaling Which of the following is the heterodimer protein ?

 A) Igalpha & Igbeta - Ans

 B) Igmicto&Iggama

 C)Igalpha&Iggama

 D) None

47) Multiple myeloma is characterized by excessive production of immunoglobulin and presence of light chain in urine.which following cells are responsible for the production of immunoglobulin.

A) T cells

B) B cells

C) Plasma cells - Ans

D) none

48) What is the life of the effector cells of the immune system?

A) A few weeks

B) A few days - Ans

C) A few months

D) A few years

49) Which of the following sets include all the types of T-cells?

A) Killer cells and Helper cells

B) Suppressor and Cytotoxic cells

C) Depressor cells, Helper cells and Memory cells

D) Killer cells, Helper cells, Suppressor cells and Memory cells. - Ans